BioParity.UFO / UAP research

50 papers for “Research methods”

Results

PaperS1287

Unidentified aerial phenomena I. Observations of events

B.E. Zhilyaev, V.N. Petukhov, V.M. Reshetnyk. arxiv.org. August 23, 2022.

Zhilyaev and colleagues report daytime imaging, angular motion and brightness variation. Their dark-object distances depend on assumed albedo and atmospheric scattering; derived sizes and extreme speeds inherit those assumptions. Moon and water-tower comparisons offer limited calibration checks. A separate two-station claim depends on synchronization and matching the same object. These reported measurements do not establish craft identity or extraterrestrial origin.

Supplied v1 text and eight native layouts reviewed; raw observations unresolved
PaperS7700

Postmitotic G1 phase survivin drives mitogen-independent cell division of B lymphocytes

Amit Singh, Matthew H Spitzer, Jaimy P Joy, Mary Kaileh, Xiang Qiu, Garry P Nolan, Ranjan Sen. pmc.ncbi.nlm.nih.gov. April 27, 2022.

This mouse-cell and laboratory-cell study examines continued B-cell division after removal of overt stimulation. Perturbation findings support a survivin-associated role within these models, while sufficiency and physiological generalization remain unestablished. Nolan contributed research and analytic tools; work-level public NIH/NIA support does not establish a classified or UAP approach.

Complete specialist supplied XML text; native apparatus unreviewed
PaperS7696

Variation of Immune Cell Responses in Humans Reveals Sex-Specific Coordinated Signaling Across Cell Types

Gabriela K. Fragiadakis, Zachary B. Bjornson-Hooper, Deepthi Madhireddy, Karen Sachs, Han Chen, David R. McIlwain, Matthew H. Spitzer, Sean C. Bendall, Garry P. Nolan. pmc.ncbi.nlm.nih.gov. March 28, 2022.

This healthy-donor study describes correlated immune responses and sex-associated differences within one cohort. Its reported prediction tests use donors from that same cohort; clinical or causal conclusions are not established. Root reviewed results, discussion, captions and declarations, with the entire Methods section excluded. FDA contracts are acknowledged at work level without identifying Nolan as their individual recipient. Nolan advised and edited the study; these public acknowledgements do not establish a classified UAP approach.

Partial root supplied XML text; Methods excluded
PaperS7483

Subcortical Brain Morphometry Differences between Adults with Autism Spectrum Disorder and Schizophrenia

Akila Weerasekera, Adrian Ion-Mărgineanu, Garry Nolan, Maria Mody. ebi.ac.uk. March 25, 2022.

Weerasekera, Nolan and colleagues compare brain-region measurements within separate autism and schizophrenia datasets. The exploratory findings have scanner, selection and interpretation limits, including disagreements between the paper’s prose, tables and figures.

Paper text, tables and figures read
PaperS7761

Kepler-1708 b-i is likely undetectable with HST

Ben Cassese, David Kipping. arxiv.org. March 24, 2022.

A simulation estimates HST recovery if the proposed Kepler-1708 moon exists. Seven of75 trials meet all requirements; conditional10±3% detectability is separate from the probability a moon exists. Optimistic systematics and JWST forecasts remain assumptions, with no independent detection or UAP claim.

Full supplied v2 manuscript; originals and simulations unverified
PaperS7703

A Comprehensive Atlas of Immunological Differences Between Humans, Mice, and Non-Human Primates

Zachary B Bjornson-Hooper, Gabriela K Fragiadakis, Matthew H Spitzer, Han Chen, Deepthi Madhireddy, Kevin Hu, Kelly Lundsten, David R McIlwain, Garry P Nolan. pmc.ncbi.nlm.nih.gov. March 11, 2022.

This comparative immune atlas describes differences among sampled humans, mice and non-human primates. Mouse blood was pooled into six tubes, and the human dataset overlaps a companion study. Selected differences face antibody-affinity and unexplained denominator limits. Nolan advised the study and edited the manuscript. FDA/NIH support is acknowledged without identifying all individual award recipients; it does not establish a UAP programme or private approach. Review excludes operational biological sections, Discussion and Methods.

Partial specialist XML; operational sections and Methods excluded
PaperS7759

An Exomoon Survey of 70 Cool Giant Exoplanets and the New Candidate Kepler-1708 b-i

David Kipping, Steve Bryson, Chris Burke, Jessie Christiansen, Kevin Hardegree-Ullman, Billy Quarles, Brad Hansen, Judit Szulágyi, Alex Teachey. arxiv.org. January 12, 2022.

A survey of70 cool giant planets reports a tentative exomoon candidate. Two transits and dependent treatments of Kepler data leave ordinary noise, blend and other-planet alternatives. Statistical planet validation and moon tests are separate; this is astronomy background, with no life or UAP detection.

Full supplied v1 manuscript; original and model checks remain open
PaperS7688

Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

Darci Phillips, Magdalena Matusiak, Belén Rivero Gutierrez, Salil S Bhate, Graham L Barlow, Sizun Jiang, Janos Demeter, Kimberly S Smythe, Robert H Pierce, Steven P Fling, Nirasha Ramchurren, Martin A Cheever, Yury Goltsev, Robert B West, Michael S Khodadoust, Youn H Kim, Christian M Schürch, Garry P Nolan. ebi.ac.uk. November 18, 2021.

This observational tissue analysis links immune-cell topography to pembrolizumab response in14selected lymphoma patients from an earlier24-patient trial. Seventy regions and large cell counts remain nested within those patients. Assay validation and resampling reuse the same cohort, without an independent clinical test. Several abundance and signature measures were null; the proposed chemokine mechanism is not causally demonstrated. Nolan is a corresponding coauthor/joint supervisor. Published government grants and commercial/patent disclosures remain attributed, without establishing a classified approach or UAP programme.

Complete specialist supplied XML text; native graphics unreviewed
PaperS7747

Erosion of Icy Interstellar Objects by Cosmic Rays and Implications for ‘Oumuamua

Vo Hong Minh Phan, Thiem Hoang, Abraham Loeb. arxiv.org. October 28, 2021.

Phan, Hoang and Loeb model erosion and modification of icy interstellar objects under assumed cosmic-ray, material and travel conditions. Prior observations and fits support theoretical predictions rather than new detections or demonstrated composition.

Complete supplied seven-page manuscript; conditional erosion model
PaperS7745

The Mass Budget Necessary to Explain ‘Oumuamua as a Nitrogen Iceberg

Amir Siraj, Abraham Loeb. arxiv.org. October 15, 2021.

Siraj and Loeb assess whether nitrogen-ice fragments could account for the earlier Oumuamua detection. Their conclusion depends on population and mass-budget assumptions; no new data are generated or analyzed.

Complete supplied three-page manuscript; conditional mass-budget model
PaperS7685

Subcellular localization of biomolecules and drug distribution by high-definition ion beam imaging

Xavier Rovira-Clavé, Sizun Jiang, Yunhao Bai, Bokai Zhu, Graham Barlow, Salil Bhate, Ahmet F Coskun, Guojun Han, Chin-Min Kimmy Ho, Chuck Hitzman, Shih-Yu Chen, Felice-Alessio Bava, Garry P Nolan. ebi.ac.uk. July 30, 2021.

This cultured-cell imaging study maps biomolecules and drug distribution at fine spatial scales, with limited skin-tissue validation. Small cell samples and nested voxels limit generalization; 33 fields/cells across treatment groups came from one experiment. The proposed nuclear-pore pumping mechanism is an interpretation, without a demonstrated causal intervention or clinical outcome. Acknowledged NIH, Army and foundation support does not establish a secret approach or UAP programme. Nolan is a corresponding author and joint supervisor. The paper declares no competing interests; native graphics, supplements and underlying data remain unreviewed.

Complete specialist supplied XML text; native graphics unreviewed
PaperS7744

Interstellar Objects Outnumber Solar System Objects in the Oort Cloud

Amir Siraj, Abraham Loeb. arxiv.org. July 22, 2021.

Siraj and Loeb infer a potentially large interstellar population from prior observations and population assumptions. The paper introduces no new data; selection, size distributions and model sensitivity limit its abundance estimates.

Complete supplied four-page manuscript; conditional abundance model

A curated public selection. Source review describes what was read; it does not establish that a claim is true. Our research approach