Results

PaperS7579

Early reprogramming regulators identified by prospective isolation and mass cytometry

Ernesto Lujan, Eli R. Zunder, Yi Han Ng, Isabel N. Goronzy, Garry P. Nolan, Marius Wernig. ebi.ac.uk. April 1, 2015.

A mouse-cell study associates early reprogramming with a transient marker state, while showing that marker usefulness changes with time and model. Bulk colonies and unique reprogramming events are different outcomes. Limited replication, negative controls and speculative human extension remain explicit. The supplied manuscript text is read; full diagrams, tables and publisher corrections remain incomplete.

Complete supplied manuscript text read; meaningful apparatus partial
PaperS7563

Joint Modeling and Registration of Cell Populations in Cohorts of High-Dimensional Flow Cytometric Data

Saumyadipta Pyne, Sharon X. Lee, Kui Wang, Jonathan Irish, Pablo Tamayo, Marc-Danie Nazaire, Tarn Duong, Shu-Kay Ng, David Hafler, Ronald Levy, Garry P. Nolan, Jill Mesirov, Geoffrey J. McLachlan. ebi.ac.uk. July 1, 2014.

JCM models and registers cell populations across preprocessed flow-cytometry samples. Its demonstrations reuse three prior datasets, with manual gates, selected panels and selected benchmark samples. The implemented model restricts the general formulation. Exploratory results and nested cells do not establish prospective clinical prediction or independent replication. Nolan contributed materials, tools and writing. Source inconsistencies in timing, marker counts, tables, references and equations remain unresolved.

Complete supplied main and static supplements read
PodcastS7519

Pathology professor and UAP expert on impact of Spielberg's "Disclosure Day"

Garry Nolan, CBS News interviewer (unmapped). ufopedia.fyi.

Nolan describes material supplied through Vallee and possible explanations for its composition, while saying it is not proof. He discusses hoped-for behind-the-scenes access. The supplied interview establishes neither a new government approach nor access to those additional materials.

Supplied transcript text read
ReportS7708

NIH RePORTER metadata for 3U19AI100627-09S2

National Institutes of Health. api.reporter.nih.gov.

Official NIH metadata returns two FY2021 application records for 3U19AI100627-09S2, both naming Scripps as recipient and the same amount. Their contact PIs are Garry P. Nolan and Richard J. Ulevitch; Sage appears in neither PI list. Shared identifiers and differing dates do not establish two independent awards or their administrative relationship. The paper’s Sage/Nolan support acknowledgement is preserved as a different fact from registered PI metadata. No classified approach, agency adoption or UAP involvement is established.

Official award metadata only; scientific and award bodies unreviewed
PaperS7678

Annotation-free discovery of disease-relevant cells in single-cell datasets

Erin Craig, Timothy J Keyes, Jolanda Sarno, Jeremy P D’Silva, Pablo Domizi, Maxim Zaslavsky, Albert Tsai, David Glass, Garry P Nolan, Trevor Hastie, Robert Tibshirani, Kara L Davis. ebi.ac.uk. August 27, 2025.

This Nolan-coauthored computational study estimates disease-associated cells using patient disease labels and a healthy baseline, without requiring expert cell annotations. Reported leukemia examples support a research method, with stronger expert-label benchmarks, small patient cohorts and assumptions that limit interpretation. Millions of measured cells do not imply millions of independent patients. Disclosed NIH support does not establish a classified programme or UAP access.

Complete supplied XML text; graphics, algorithms and supplements unreviewed
PaperS7692

Organization of the human intestine at single-cell resolution

John W. Hickey, Winston R. Becker, Stephanie A. Nevins, Aaron Horning, Almudena Espin Perez, Chenchen Zhu, Bokai Zhu, Bei Wei, Roxanne Chiu, Derek C. Chen, Daniel L. Cotter, Edward D. Esplin, Annika K. Weimer, Chiara Caraccio, Vishal Venkataraaman, Christian M. Schürch, Sarah Black, Maria Brbić, Kaidi Cao, Shuxiao Chen, Weiruo Zhang, Emma Monte, Nancy R. Zhang, Zongming Ma, Jure Leskovec, Zhengyan Zhang, Shin Lin, Teri Longacre, Sylvia K. Plevritis, Yiing Lin, Garry P. Nolan, William J. Greenleaf, Michael Snyder. pmc.ncbi.nlm.nih.gov. July 19, 2023.

This healthy-adult intestine atlas describes regional tissue composition and spatial organization in nine donors. Millions of cells and regional sections remain nested within donors. Predicted signalling and regulatory associations are hypotheses; subset validation overlaps one donor and does not establish a clinical or causal mechanism. Nolan is a corresponding coauthor and supervisor. Published funding and commercial disclosures provide ordinary research context, without establishing a classified approach or UAP programme.

Complete specialist supplied XML text; native apparatus unreviewed
PaperS7685

Subcellular localization of biomolecules and drug distribution by high-definition ion beam imaging

Xavier Rovira-Clavé, Sizun Jiang, Yunhao Bai, Bokai Zhu, Graham Barlow, Salil Bhate, Ahmet F Coskun, Guojun Han, Chin-Min Kimmy Ho, Chuck Hitzman, Shih-Yu Chen, Felice-Alessio Bava, Garry P Nolan. ebi.ac.uk. July 30, 2021.

This cultured-cell imaging study maps biomolecules and drug distribution at fine spatial scales, with limited skin-tissue validation. Small cell samples and nested voxels limit generalization; 33 fields/cells across treatment groups came from one experiment. The proposed nuclear-pore pumping mechanism is an interpretation, without a demonstrated causal intervention or clinical outcome. Acknowledged NIH, Army and foundation support does not establish a secret approach or UAP programme. Nolan is a corresponding author and joint supervisor. The paper declares no competing interests; native graphics, supplements and underlying data remain unreviewed.

Complete specialist supplied XML text; native graphics unreviewed
PaperS7624

Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front

Christian M Schürch, Salil S Bhate, Graham L Barlow, Darci J Phillips, Luca Noti, Inti Zlobec, Pauline Chu, Sarah Black, Janos Demeter, David R McIlwain, Shigemi Kinoshita, Nikolay Samusik, Yury Goltsev, Garry P Nolan. ebi.ac.uk. September 3, 2020.

The authors analyze spatial immune patterns in selected colorectal-cancer tissue. Thirty-five patients supply140 dependent tissue cores; repeated cells, regions and holdouts do not create new cohorts. Survival findings and correlation-based “communication” are exploratory. A linked correction adds Shigemi Kinoshita to the author list. No clinical efficacy or UAP finding is established.

Complete supplied main, figures and correction; bounded supplementary review
PaperS7613

Cellular Signaling Analysis shows antiviral, ribavirin-mediated ribosomal signaling modulation

Xianting Ding, Peter O Krutzik, Amir Ali Ghaffari, Yixiu Zhaozhi, Daniel Miranda Jr, Genhong Cheng, Chih-Ming Ho, Garry P Nolan, David Jesse Sanchez. ebi.ac.uk. September 9, 2019.

The authors connect antiviral treatment, infection and ribosomal signaling in selected cell assays and a short mouse model. Timing, inadequate low-dose response, broad effects at higher doses, declining viability and delayed animal results qualify the mechanism. These findings do not demonstrate treatment benefit or safety in people.

Complete supplied main and meaningful images; raw study unreviewed
PaperS7593

Commonly Occurring Cell Subsets in High-Grade Serous Ovarian Tumors Identified by Single-Cell Mass Cytometry

Veronica D. Gonzalez, Nikolay Samusik, Tiffany J. Chen, Erica S. Savig, Nima Aghaeepour, David A. Quigley, Ying-Wen Huang, Valeria Giangarrà, Alexander D. Borowsky, Neil E. Hubbard, Shih-Yu Chen, Guojun Han, Alan Ashworth, Thomas J. Kipps, Jonathan S. Berek, Garry P. Nolan, Wendy J. Fantl. ebi.ac.uk. February 13, 2018.

Mass cytometry identifies tumor-cell subsets and outcome associations in a small ovarian-cancer cohort. Dominant and hybrid clusters did not individually correlate with relapse. Same-cohort marker selection and missing independent validation limit interpretation; cell-line response is not demonstrated patient benefit.

Supplied author manuscript read; figures and supplement missing
PaperS7676

The commitment of the human cell atlas to humanity

Ido Amit and coauthors (including Garry Nolan). ebi.ac.uk. November 20, 2024.

This HCA perspective, coauthored by Garry Nolan, describes equitable participation, local research leadership, informed consent, privacy and open versus managed data access. Its claims concern consortium aims and reported activities, rather than a clinical trial or proof of universal benefits. Public scientific collaboration and institutional affiliations do not demonstrate a secret government approach or UAP programme.

Complete supplied XML text; original figure pixels unreviewed
ReportS7681

FDA OCET Overview of the BAA — selected contract metadata, December 6, 2022

Robert Orr, U.S. Food and Drug Administration. fda.gov. December 6, 2022.

Robert Orr’s FDA presentation publicly describes a 2017 modification of contract HHSF223201610018C and links 75F40120C00176 to a collaboration studying COVID-19 illness in diverse populations. These identifiers match contracts acknowledged for Nolan in MaxFuse. The slides document agency statements about public research funding; they do not name Nolan or establish secret invitations or UAP access.

Partial root native PDF text and selected layout review

A curated public selection. Source review describes what was read; it does not establish that a claim is true. Our research approach