Results

PaperS7706

High-throughput multiplexed serology via the mass-spectrometric analysis of isotopically barcoded beads

Alexandros P Drainas, David R McIlwain, Alec Dallas, Theresa Chu, Antonio Delgado-González, Maya Baron, Maria Angulo-Ibáñez, Angelica Trejo, Yunhao Bai, John W Hickey, Guolan Lu, Scott Lu, Jesus Pineda-Ramirez, Khamal Anglin, Eugene T Richardson, John C Prostko, Edwin Frias, Venice Servellita, Noah Brazer, Charles Y Chiu, Michael J Peluso, Jeffrey N Martin, Oliver F Wirz, Tho D Pham, Scott D Boyd, J Daniel Kelly, Julien Sage, Garry P Nolan, Xavier Rovira-Clavé. pmc.ncbi.nlm.nih.gov. February 12, 2025.

This serology technology article was reviewed only for descriptive background, author roles, funding, disclosures and bibliography. Aggregate assay counts do not establish independent participant counts or clinical performance; their target-count arithmetic remains unresolved within this scope. Nolan shares an acknowledged NIH award with Julien Sage and is a corresponding author/joint supervisor. Patent and company interests are declared. Results, Discussion, Methods and figure captions remain excluded; no UAP or private-approach inference follows.

Partial descriptive XML; Results, Discussion and Methods excluded
PaperS7701

A multi-omics spatial framework for host-microbiome dissection within the intestinal tissue microenvironment

Bokai Zhu, Yunhao Bai, Yao Yu Yeo, Xiaowei Lu, Xavier Rovira-Clavé, Han Chen, Jason Yeung, Dingani Nkosi, Jonathan Glickman, Antonio Delgado-Gonzalez, Georg K. Gerber, Mike Angelo, Alex K. Shalek, Garry P. Nolan, Sizun Jiang. pmc.ncbi.nlm.nih.gov. January 31, 2025.

This mouse-intestine study combines spatial imaging, gene-expression and glycan measurements to examine inflammation-associated patterns. Its many cells and regions come from eight main-cohort mice, and correlations do not establish microbial causation or clinical performance. Nolan is a corresponding author and joint supervisor. The reviewed scope is partial, with biological-validation sections and Methods excluded; public support and commercial disclosures do not establish a UAP programme or private approach.

Partial specialist XML; validation and Methods excluded
PaperS7692

Organization of the human intestine at single-cell resolution

John W. Hickey, Winston R. Becker, Stephanie A. Nevins, Aaron Horning, Almudena Espin Perez, Chenchen Zhu, Bokai Zhu, Bei Wei, Roxanne Chiu, Derek C. Chen, Daniel L. Cotter, Edward D. Esplin, Annika K. Weimer, Chiara Caraccio, Vishal Venkataraaman, Christian M. Schürch, Sarah Black, Maria Brbić, Kaidi Cao, Shuxiao Chen, Weiruo Zhang, Emma Monte, Nancy R. Zhang, Zongming Ma, Jure Leskovec, Zhengyan Zhang, Shin Lin, Teri Longacre, Sylvia K. Plevritis, Yiing Lin, Garry P. Nolan, William J. Greenleaf, Michael Snyder. pmc.ncbi.nlm.nih.gov. July 19, 2023.

This healthy-adult intestine atlas describes regional tissue composition and spatial organization in nine donors. Millions of cells and regional sections remain nested within donors. Predicted signalling and regulatory associations are hypotheses; subset validation overlaps one donor and does not establish a clinical or causal mechanism. Nolan is a corresponding coauthor and supervisor. Published funding and commercial disclosures provide ordinary research context, without establishing a classified approach or UAP programme.

Complete specialist supplied XML text; native apparatus unreviewed
PaperS7688

Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

Darci Phillips, Magdalena Matusiak, Belén Rivero Gutierrez, Salil S Bhate, Graham L Barlow, Sizun Jiang, Janos Demeter, Kimberly S Smythe, Robert H Pierce, Steven P Fling, Nirasha Ramchurren, Martin A Cheever, Yury Goltsev, Robert B West, Michael S Khodadoust, Youn H Kim, Christian M Schürch, Garry P Nolan. ebi.ac.uk. November 18, 2021.

This observational tissue analysis links immune-cell topography to pembrolizumab response in14selected lymphoma patients from an earlier24-patient trial. Seventy regions and large cell counts remain nested within those patients. Assay validation and resampling reuse the same cohort, without an independent clinical test. Several abundance and signature measures were null; the proposed chemokine mechanism is not causally demonstrated. Nolan is a corresponding coauthor/joint supervisor. Published government grants and commercial/patent disclosures remain attributed, without establishing a classified approach or UAP programme.

Complete specialist supplied XML text; native graphics unreviewed
PaperS7618

Hans Kammler, Hitler’s Last Hope, in American Hands

Frank Döbert, Rainer Karlsch. wilsoncenter.org. August 2019.

Döbert and Karlsch argue that archival references establish Kammler’s capture by American forces. Their paper combines a reported held-personnel list, later interrogation arrangements and family accounts. It also leaves his destination, subsequent disclosures and fate unresolved. The capture argument remains attributed to the authors; ordinary wartime weapons history does not establish UAP exploitation.

Complete supplied paper text; targeted layouts and original-record gaps
PaperS7565

Role for polo-like kinase 4 in mediation of cytokinesis

Michael F Press, Bin Xie, Simon Davenport, Yu Zhou, Roberta Guzman, Garry P Nolan, Neil O’Brien, Michael Palazzolo, Tak W Mak, Joan S Brugge, Dennis J Slamon. ebi.ac.uk. May 16, 2019.

A cell-line study examines PLK4 localization and cytokinesis through antibody, genetic and inhibitor assays. The cleavage mechanism and cellular inhibitor specificity remain uncertain. Figure captions, sample panels and starting-cell counts conflict, while some replicate and animal-method details are missing. Nolan contributed reagents and analytic tools. Funding, intellectual property and commercial disclosures are specifically attributed.

Complete supplied main and static appendix read; movies unviewed

A curated public selection. Source review describes what was read; it does not establish that a claim is true. Our research approach