BioParity.UFO / UAP research

2 papers for “Immune composition”

Results

PaperS7626

Sex Differences in the Blood Transcriptome Identify Robust Changes in Immune Cell Proportions with Aging and Influenza Infection

Erika Bongen, Haley Lucian, Avani Khatri, Gabriela K Fragiadakis, Zachary B Bjornson, Garry P Nolan, Paul J Utz, Purvesh Khatri. ebi.ac.uk. November 12, 2019.

The authors derive a144-gene sex-expression signature from public cohorts and explore age, inferred immune composition and influenza response. Cohort reuse and repeated observations limit independent sample counts. Associations do not establish hormone mechanisms or clinical prediction. A retraction linked inside a cited reference concerns that older paper’s epistasis interpretation; it is not a retraction of this study.

Complete supplied main, tables, meaningful figures and eight supplemental pages
PaperS7625

Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma

Andrew L Ji, Adam J Rubin, Kim Thrane, Sizun Jiang, David L Reynolds, Robin M Meyers, Margaret G Guo, Benson M George, Annelie Mollbrink, Joseph Bergenstråhle, Ludvig Larsson, Yunhao Bai, Bokai Zhu, Aparna Bhaduri, Jordan M Meyers, Xavier Rovira-Clavé, S Tyler Hollmig, Sumaira Z Aasi, Garry P Nolan, Joakim Lundeberg, Paul A Khavari. ebi.ac.uk. July 23, 2020.

The authors combine sequencing and imaging to describe selected squamous-cancer tissue, including a tumour-specific keratinocyte population. Cells, spots and fields depend on small patient subsets. Predicted interactions and proximity do not establish causal immune suppression. A linked correction repairs duplicated and mislabeled figure material; its unchanged-conclusions statement is attributed to the authors.

Complete supplied main, correction, S5 cells and S3 signature cells; remaining gaps

A curated public selection. Source review describes what was read; it does not establish that a claim is true. Our research approach