{"apiVersion":"1","version":"sha256:faade27e0b75b2aca6311142ff65347b4dacc153e8d28cbdf0e8a237319331f9","data":{"id":"S7700","title":"Postmitotic G1 phase survivin drives mitogen-independent cell division of B lymphocytes","authors":["Amit Singh","Matthew H Spitzer","Jaimy P Joy","Mary Kaileh","Xiang Qiu","Garry P Nolan","Ranjan Sen"],"publishedDate":"2022-04-27","format":"Paper","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9170024/","summary":"This mouse-cell and laboratory-cell study examines continued B-cell division after removal of overt stimulation. Perturbation findings support a survivin-associated role within these models, while sufficiency and physiological generalization remain unestablished. Nolan contributed research and analytic tools; work-level public NIH/NIA support does not establish a classified or UAP approach.","subjects":["Imaging","Research methods"],"people":["Garry Nolan"],"review":{"label":"Complete specialist supplied XML text; native apparatus unreviewed","scope":"Specialist read all 61,128 supplied XML characters in eight contiguous returns, including seven captions and 57 references. Root reviewed the complete analytical packet; no primary-text or pixel reread.","gaps":["Unique mouse count, sex and assay overlap unestablished; selected cells/nodes are dependent measurements, not patients.","Survival support differs from renewed stimulation; not all cells divide. Excess cell death confounds a pathway-inhibitor test.","Drug selectivity, target rescue, sufficiency, external validation and in-vivo/clinical relevance remain limited or untested.","Caption/prose units, significance legends and fraction labels conflict; no silent correction.","NIH/NIA support is work-level with no named individual recipient or award ID.","Seven graphics, detailed SI, data, code, cited originals and version history unreviewed."]},"familyId":"NOLAN-SURVIVIN-2022-2115567119","citationUrl":"https://bioparity.io/sources/S7700","citation":"Amit Singh, Matthew H Spitzer, Jaimy P Joy, Mary Kaileh, Xiang Qiu, Garry P Nolan, Ranjan Sen. Postmitotic G1 phase survivin drives mitogen-independent cell division of B lymphocytes. April 27, 2022. BioParity S7700. https://bioparity.io/sources/S7700"}}