{"apiVersion":"1","version":"sha256:faade27e0b75b2aca6311142ff65347b4dacc153e8d28cbdf0e8a237319331f9","data":{"id":"S7520","title":"Highly multiplexed spatial profiling with CODEX: bioinformatic analysis and application in human disease","authors":["Wilson Kuswanto","Garry Nolan","Guolan Lu"],"publishedDate":"2022-11-21","format":"Paper","url":"https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9684921/fullTextXML","summary":"This narrative review explains CODEX tissue imaging, processing limitations and spatial analysis. Its disease examples summarize cited studies; they do not supply a new patient cohort or independent replication. The review calls for stronger causal and prospective validation.","subjects":["Scientific background","Spatial imaging","Research limitations"],"people":["Garry Nolan"],"review":{"label":"Supplied review text and qualified figures read","scope":"All 118 supplied XML units, 50 reference entries and both tables were read. Two native conceptual figures were inspected; tiny illustrative matrix characters remain partly unreadable. Online publication November 21, 2022 and January 2023 issue date are distinct.","gaps":["Complete publisher facsimile, underlying cited study bodies, raw cohorts and experimental datasets were not reviewed.","Spatial association is not causation or clinical guidance. Tools were not executed or benchmarked currently; patent and company-interest disclosures and internal citation/version discrepancies remain explicit. This is scholarly background, without a UAP injury or government programme finding."]},"familyId":"10.1007/s00281-022-00974-0","citationUrl":"https://bioparity.io/sources/S7520","citation":"Wilson Kuswanto, Garry Nolan, Guolan Lu. Highly multiplexed spatial profiling with CODEX: bioinformatic analysis and application in human disease. November 21, 2022. BioParity S7520. https://bioparity.io/sources/S7520"}}