{"apiVersion":"1","version":"sha256:faade27e0b75b2aca6311142ff65347b4dacc153e8d28cbdf0e8a237319331f9","data":{"id":"S7500","title":"Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models","authors":["Bahareh Ajami","Nikolay Samusik","Peter Wieghofer","Peggy P. Ho","Andrea Crotti","Zach Bjornson","Marco Prinz","Wendy J. Fantl","Garry P. Nolan","Lawrence Steinman"],"publishedDate":"2018-03-05","format":"Paper","url":"https://med.stanford.edu/content/dam/sm/urology/JJimages/publications/Single-cell-mass-cytometry-reveals-distinct-populations-of-brain-myeloid-cells-in-mouse-neuroinflammation-and-neurodegeneration-models.pdf","summary":"Ajami, Nolan and colleagues analyse brain myeloid populations in mouse disease models. Mouse treatment findings do not establish human therapy or UAP-related illness. Pooling, statistical assumptions and inconsistencies constrain interpretation.","subjects":["Garry Nolan research","Brain immunology","Research methods"],"people":["Garry Nolan"],"review":{"label":"Paper, methods, figures and checklist read","scope":"All 16 supplied pages were read and visually inspected: printed pages 541–551, methods, reporting summary, six main figures and 62 references. Online publication is March 5, 2018; issue date is April.","gaps":["Separate supplementary figures 1–13, tables 1–2, underlying FCS/raw data, code execution and independent replication were not reviewed.","Cell counts are not independent animal counts. Prophylaxis day 0/day 1 and supplementary panel mappings disagree. Nolan advised design, analysis and interpretation; grant acknowledgments do not establish a secret programme."]},"familyId":"DOI-10.1038-S41593-018-0100-X","citationUrl":"https://bioparity.io/sources/S7500","citation":"Bahareh Ajami, Nikolay Samusik, Peter Wieghofer, Peggy P. Ho, Andrea Crotti, Zach Bjornson, Marco Prinz, Wendy J. Fantl, Garry P. Nolan, Lawrence Steinman. Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models. March 5, 2018. BioParity S7500. https://bioparity.io/sources/S7500"}}